To understand what AJAX applications are, see http://en.wikipedia.org/wiki/AJAX for a generic description.
See http://en.wikipedia.org/wiki/AJAX for a general description of the benefits of an AJAX application.
In the Framework, AJAX applications offer:
Compared to WAM applications, AJAX application development requires an extended skill set and usually longer development times.
Also, AJAX applications generally produce higher web and application server hit rates. The requests are usually simpler but made more often. This changes the profile of the performance load on your web and application servers. This is a very important consideration in your application design.
Generally, you should only use AJAX applications when the additional cost of developing them is less than the value of the benefit they deliver (the problem of course is in assessing the true value of the benefit they deliver).
A typical Framework-WEB application should mainly consist of WAM functions, with the occasional AJAX routine used in selected application areas.
You might use AJAX: