If the partition on the server is RDMLX enabled and you are going to use RDMLX server side components, functions or files within your Framework application, you should select this option.
Select this option for example when your VLF application might be using CALL_SERVER_FUNCTION to run an RDMLX function or accessing an RDMLX table on the server.
If this setting is selected, the connection to the server uses the built in function DEFINE_ANY_SERVER. See the documentation for the restrictions for the built in function in the Technical Reference Guide.
This property is in the Server Details tab.